The NAPLEX Top 300 — Daily Challenge is a free crossword game for learning the brand and generic names of the most commonly prescribed medications. It's built for PharmD students, pharmacy technicians, and anyone studying for the NAPLEX or PTCB board exams who needs to memorize the Top 200 and Top 300 drugs. A fresh mixed puzzle is generated every day, and you can also drill specific therapeutic classes with over 600 medications across 19 categories.
Every clue gives you one drug name plus its pharmacologic class, and you fill in the matching brand or generic name. Clear all the puzzles in a therapeutic class to unlock a boss round covering every term in that section. Use the ⇄ button to flip between guessing brand names from generics, or generics from brands — active recall that makes drug-name pairs stick for exam day.
Yes — it's completely free, with no account or sign-up required. Open it in any browser and start playing.
Over 600 medications drawn from the Top 200–300 most prescribed drugs, organized into 19 therapeutic classes including cardiovascular, diabetes, antibiotics, oncology, neurology, psychiatry, respiratory, and gastrointestinal.
Instead of re-reading a list, you retrieve each name from memory to fill the grid. This active-recall approach is a proven, faster way to lock in brand/generic pairs for the NAPLEX and PTCB exams.
Yes. Open the Sections menu to focus on a single class — for example antihypertensives, antidiabetics, or antibiotics — and work through it puzzle by puzzle, then beat the boss round.
No. This is an independent study tool, not affiliated with, endorsed by, or sponsored by the National Association of Boards of Pharmacy (NABP). "NAPLEX" is a registered trademark of the NABP.
Any modern browser on phone, tablet, or desktop. The crossword grid automatically scales to fit your screen.
For study and general reference only; always confirm drug information against authoritative clinical resources before use.